Malaysia Veterinary Forum (Archive)

nurul nueha · Joined: 20 Sep 2006 Posts: 13 Location: iium,kuala lumpur

there is a creamy thingy come out from my cat anus.
and i believe that this thing hppend after she mated wif my male cat.
because after my vet gave a treatment to her last month, the creamy thingy still come out. is it pyometra or what? help me please.

Dr Nat · Joined: 07 Dec 2005 Posts: 1834 Location: Klang Valley

Pyometra is only ONE of the possibilities. Have you brough the cat back for a re-examination?

nurul nueha · Joined: 20 Sep 2006 Posts: 13 Location: iium,kuala lumpur

Dr Nat wrote: Pyometra is only ONE of the possibilities. Have you brough the cat back for a re-examination?

hye doc.thanks for ur reply.
actually,yesterday my mom have brought our cat to Dr Gill in Penang.
this is our first visit to Gill's place.
so,he asked my mum about the medicine that d previous doc gave to us.
but my mum dont really know the exact prescriptions.
so, Dr Gill gave us an antibiotic to be consume for 10 days.and he asked us to come back after that 10 days for another check up n vaccination.
and come again after another 10 days for spaying.

BUT, after 2 days my cat consume that antibiotic, that creamy thing come out from her anus. my mum called Dr Gill, and he said wait until d 3rd day, then call him if this thing come out again.
today is the 3rd day my cat consume that antibiotic and she seems ok la..
no creamy discharge.

anyway,what is pyometra doc?

TiaraBionca · Joined: 09 Sep 2006 Posts: 54 Location: Kuala Lumpur

Hi Nurul,
Welcome to this forum. I'm glad to hear she is recovering. keep us posted on her progress ya. Nice meeting you and have a nice day.

I too just learned about pyometra after reading about your question and went searching on internet. One thing great about this forum, you get to acquire free advise from Doctors on this forum and attain lots of knowledge about feline behavior and diseases

By the way below are the link about pyometra. Hope you find it informative.
http://www.gdhfa.org/Pyometra.htm

Dr Nat · Joined: 07 Dec 2005 Posts: 1834 Location: Klang Valley

Sorry, I didn't notice at first. Did you say creamy white thing coming out from the ANUS or VAGINA? If it really is anus, then its not pyometra.

Pyometra is an infection of the womb. (Er, just curious, if you are not sure what is pyometra, how did you come up with pyometra in the first place?). Pyometra means that the uterus is all full of pus. This usually occurs in the dog, and is quite rare in cats. And sometimes, cats can have pyometra but show no signs at all.

If you are not sure what it is your cat has, call up your vet and ask for his diagnosis, or what it is he suspects. (Usually the vet will come up with a whole list of possibilities, and from there, pick the most likely one to treat).

nurul nueha · Joined: 20 Sep 2006 Posts: 13 Location: iium,kuala lumpur

TiaraBionca wrote: Hi Nurul,
Welcome to this forum. I'm glad to hear she is recovering. keep us posted on her progress ya. Nice meeting you and have a nice day.

I too just learned about pyometra after reading about your question and went searching on internet. One thing great about this forum, you get to acquire free advise from Doctors on this forum and attain lots of knowledge about feline behavior and diseases

By the way below are the link about pyometra. Hope you find it informative.
http://www.gdhfa.org/Pyometra.htm

hye tiarabionca~ yea,she's recovering.i hope she'll be fully recover. nice meeting u to frens, n u too have a wonderful weekend.
about the link, i'm trying to browse it rite now.
i'll post her progress in here.don worry.. =)
see ya soon~

nurul nueha · Joined: 20 Sep 2006 Posts: 13 Location: iium,kuala lumpur

Dr Nat wrote: Sorry, I didn't notice at first. Did you say creamy white thing coming out from the ANUS or VAGINA? If it really is anus, then its not pyometra.

Pyometra is an infection of the womb. (Er, just curious, if you are not sure what is pyometra, how did you come up with pyometra in the first place?). Pyometra means that the uterus is all full of pus. This usually occurs in the dog, and is quite rare in cats. And sometimes, cats can have pyometra but show no signs at all.

If you are not sure what it is your cat has, call up your vet and ask for his diagnosis, or what it is he suspects. (Usually the vet will come up with a whole list of possibilities, and from there, pick the most likely one to treat).

sorry Dr nat.
me too, i dunno how to differentiate between anus n vagina. =(
which is which?
by the way,i got the pyometra term, from a fen in california.
she just suspected that it is pyometra. [after listening to d whole story]

ok doc, i'll try to ask for Dr Gill diagnosis.

Dr Nat · Joined: 07 Dec 2005 Posts: 1834 Location: Klang Valley

Quote: i dunno how to differentiate between anus n vagina.
Imagine the cat infront of you with the butt facing you. Lift up her tail. The top one is her anus, the bottom one (that looks more like a slit) is her vagina. If there's testicles in between, then its a male. Haha..

I cant find a good picture to show you. When I find it I'll post it up :)

nurul nueha · Joined: 20 Sep 2006 Posts: 13 Location: iium,kuala lumpur

Dr Nat wrote: Quote: i dunno how to differentiate between anus n vagina.
Imagine the cat infront of you with the butt facing you. Lift up her tail. The top one is her anus, the bottom one (that looks more like a slit) is her vagina. If there's testicles in between, then its a male. Haha..

I cant find a good picture to show you. When I find it I'll post it up :)

:cry: that creamy thingy come out from her vagina doc.
and it happnd again yesterday [saturday] even after she had consumed the antibiotics for 4 days..
mated is the problem ke doc?
usually, we left both of them dalam rumah.neither being caged nor separate.
what is ur suggestion doc?
+sigh+

Dr Chong · Joined: 12 Dec 2005 Posts: 666 Location: KL

Here is some info on pyometra quoted from the Merck Vet Manual:

Quote:
Pyometra is a hormonally mediated diestrual disorder characterized by cystic endometrial hyperplasia with secondary bacterial infection. Pyometra is reported primarily in older bitches (>5 yr old), 4-6 wks after estrus.

Etiology:
Factors associated with occurrence of pyometra include administration of longlasting progestational compounds to delay or suppress estrus, administration of estrogens to mismated bitches, and postinsemination or postcopulation infections. Progesterone promotes endometrial growth and glandular secretion while decreasing myometrial activity. Cystic endometrial hyperplasia and accumulation of uterine secretions ultimately develop and provide an excellent environment for bacterial growth. Progesterone may also inhibit the WBC response to bacterial infection. Bacteria from the normal vaginal flora or subclinical urinary tract infections are the most likely sources of uterine contamination. Escherichia coli is the most common bacterium isolated in cases of pyometra, although Staphylococcus , Streptococcus , Pseudomonas , and Proteus spp , and other bacteria also have been recovered. Because queens require copulatory stimulation to ovulate and produce progesterone from corpora lutea, pyometra is less common in queens than in bitches. Administration of medroxyprogesterone and other progestational compounds has been associated with development of pyometra in bitches and queens. Pyometra can develop in uterine tissue left after ovariohysterectomy (stump pyometra). It can also occur secondary to postpartum metritis.

By itself, estrogen does not contribute to the development of cystic endometrial hyperplasia or pyometra. However, it does increase the stimulatory effects of progesterone on the uterus. Administration of exogenous estrogens to prevent pregnancy (ie, “mismate shots”) during diestrus greatly increases the risk of developing pyometra and should be discouraged.

Clinical and Laboratory Findings:
Clinical signs are seen during diestrus (usually 4-8 wk after estrus) or after administration of exogenous progestins. The signs are variable and include lethargy, anorexia, polyuria, polydipsia, and vomiting. When the cervix is open, a purulent vulvar discharge, often containing blood, is present. When the cervix is closed, there is no discharge and the large uterus may cause abdominal distention. Signs can progress rapidly to shock and death.

Physical examination reveals lethargy, dehydration, uterine enlargement, and if the cervix is patent, a sanguineous to mucopurulent vaginal discharge. Only 20% of affected animals have a fever. Shock may be present.

The leukogram of animals with pyometra is variable and may be normal; however, leukocytosis characterized by a neutrophilia with a left shift is usual. Leukopenia may be found in animals with sepsis. A mild, normocytic, normochromic, nonregenerative anemia (PCV of 28-35%) may also develop. Hyperproteinemia due to hyperglobulinemia may be found. Results of urinalysis are variable. With E coli uterine infection, isosthenuria due to endotoxin-induced impairment of renal tubular function or to insensitivity to antidiuretic hormone (or both) may develop. A glomerulonephropathy caused by immune-complex deposition may result in proteinuria. These renal lesions are potentially reversible once the pyometra is resolved.

Diagnosis:
Pyometra should be suspected in any ill, diestrual bitch or queen, especially if polydipsia, polyuria, or vomiting is present. The diagnosis can be established from the history, physical examination, abdominal radiography, and ultrasonography. Vaginal cytology is often helpful in determining the nature of the vulvar discharge. A CBC, biochemical profile, and urinalysis help exclude other causes of polydipsia, polyuria, and vomiting; they also evaluate renal function, acid-base status, and septicemia. The uterine exudate should be cultured and sensitivity tests performed. Differential diagnoses include pregnancy and other causes of vulvar discharge, polyuria and polydipsia, and vomiting.

Treatment and Prognosis:
Ovariohysterectomy is the treatment of choice. Medical management could be considered if salvaging the reproductive potential of the bitch or queen is desired. Fluids (IV) and broad-spectrum, bactericidal antibiotics should be administered. Fluid, electrolyte, and acid-base imbalances should be corrected as quickly as possible, before ovariohysterectomy is performed. The bacterial infection is responsible for the illness and will not resolve until the uterine exudate is removed. Oral antibiotics (based on the results of the culture and sensitivity) should be continued for 7-10 days after surgery.

Medical therapy with prostaglandin F2a (PGF2α ) can be used for animals to be bred in the future, although prostaglandins are not approved in the USA for use in cats or dogs. PGF2α causes luteolysis, contraction of the myometrium, relaxation of the cervix, and expulsion of the uterine exudate. They should probably not be used in animals >8 yr old or in those not intended for breeding. The delay before clinical improvement and the many side effects of PGF2α preclude its use in a severely ill animal. PGF2α also should be used with caution in bitches or queens with a closed-cervix pyometra because of increased risk of uterine rupture. Pregnancy must be ruled out, as prostaglandins can induce abortion.

Only naturally occurring PGF2α (0.25 mg/kg, SC, sid for 5 days) should be used. Synthetic analogs (eg, cloprostenol, fluprostenol, and prostalene) are much more potent than natural PGF2α but have not been evaluated for use in dogs or cats. Broad-spectrum, bactericidal antibiotics, chosen on the basis of culture and sensitivity tests, should be given for ≥2 wk.

The side effects of PGF2α include restlessness, anxiety, panting, hypersalivation, pacing, tachycardia, vomiting, urination, and defecation. In cats, vocalization and intense grooming behavior also may be seen. These reactions disappear within 2 hr of the injection. The LD50 of PGF2α in dogs is 5.13 mg /kg. Severe ataxia, respiratory distress, and muscle tremors may be seen in queens given 5 mg/kg. If severe side effects occur, IV fluids at rates appropriate for treatment of shock are indicated. Uterine evacuation after an injection is variable.

Animals should be reexamined 2 wk after completion of medical therapy. If a sanguineous or mucopurulent vulvar discharge or uterine enlargement is still present, PGF2α therapy, using the same protocol, may be repeated; however, the prognosis for recovery is much worse. After medical therapy, the prognosis for initial resolution of the pyometra is good if the cervix is open, but guarded to poor if closed. Of those animals that respond, as many as 90% of bitches and 70% of queens with open-cervix pyometra may be fertile. Recurrence is likely; of bitches treated medically for pyometra, 70% had recurrence within 2 yr. Therefore, the animal should be bred on the next and each subsequent cycle until the desired number of puppies or kittens has been produced, and then spayed.

fhinz · Joined: 25 Aug 2006 Posts: 295 Location: KL or Miri

my cats are a bit pissy if I try to play with their tail. Their tails usually curl a bit at the end of the tail, that's why I love to play their tails, the tails are soooooo cute. So, the only time when I can see their anus and vagina (and to see if they are male or female) is when they are still kittens. At least, kittens' bites and scratches are more ticklish than hurtful.

nurul nueha · Joined: 20 Sep 2006 Posts: 13 Location: iium,kuala lumpur

i've spayed my cat.so,now she's in a very good condition.no more pyometra. n next week, i'll spay her 2 daughter. =) advice for forumers, please spay ur cat and dog; it'll save their life and we can decrease the number of stray cats. thanks to all.thanks to Dr Nat.

*credit to Dr Sarah [from Gill's vet in Penang].

Dr Nat · Joined: 07 Dec 2005 Posts: 1834 Location: Klang Valley

Good to know that she's doing well now :)